Why ENT surgery in children needs a special approach
Operations on the tonsils, adenoids, nasal septum, ears and sinuses in children are performed in reflexogenic zones, close to large blood vessels and the cranial cavities. This requires adequate pain relief, stable breathing and strict control of the child’s position on the operating table. That is why multicomponent endotracheal general anesthesia is considered the “gold standard” for most ENT operations in children.
Local anesthesia in ENT surgery: role and limitations
In Russia, local anesthesia has historically been widely used in ENT surgery, especially for adenoidectomy and tonsillectomy. Its role is now being reconsidered:
- Topical or infiltration anesthesia is used as a component of general anesthesia or for minor procedures (laser and radiofrequency operations in an outpatient setting)
- For major operations on the lymphoid ring of the throat and deep-lying structures, local anesthesia does not provide sufficient pain relief and neurovegetative protection, especially in children
In short, in children local anesthesia more often complements general anesthesia rather than serving as a standalone method for full ENT operations.
General anesthesia: combined endotracheal anesthesia
- Induction — by inhalation (a mask with an N₂O/O₂ gas mixture and a volatile anesthetic such as sevoflurane or isoflurane) or intravenously (propofol and others) — depending on the child’s age, venous access and the team’s experience
- Maintenance — inhalation anesthesia (N₂O:O₂ in various ratios with sevoflurane or isoflurane) or an intravenous propofol infusion, often combined
- Analgesia — provided by opioids (fentanyl as a bolus or infusion) and non-steroidal anti-inflammatory drugs
- Airway — tracheal intubation ensures free, controlled breathing and protects the airway from blood and secretions
This approach is considered the safest and most controllable for most ENT operations in children.
Mask inhalation anesthesia
For small, short procedures (for example, placing or removing a tympanostomy tube), mask anesthesia without intubation may be used. Short-acting inhaled anesthetics are used for up to 30 minutes, which suits brief procedures in children. However, in young children and when the risk of airway obstruction is higher, anesthesiologists increasingly prefer endotracheal anesthesia.
Intravenous pain relief regimens
A continuous propofol infusion with oxygen or a gas mixture (N₂O + O₂) makes it possible to perform long operations with a controlled depth of anesthesia. Opioids (fentanyl) are given as a bolus or infusion to provide a full analgesic component. Combining inhalation and intravenous anesthesia gives the flexibility to adapt to the length and complexity of the operation.
Premedication and prevention of postoperative pain and nausea
- Premedication — oral midazolam or intranasal dexmedetomidine, sometimes combined with other drugs, is used to reduce pre-operative stress and improve cooperation
- Postoperative pain relief — starts in the operating room: opioids, NSAIDs, paracetamol, regional blocks and local anesthetics are used
- Prevention of nausea and vomiting — antiemetics (metoclopramide, ondansetron and others) are given at induction and before the end of anesthesia
This multi-level strategy reduces the child’s discomfort after surgery and supports early recovery.
Safety and organizational requirements
- Observing the fasting period before surgery and individual planning of infusion therapy
- Full anesthesia equipment, a resuscitation kit and trained staff at the clinic
- Standardized monitoring during surgery (ECG, blood pressure, SpO₂, capnography, temperature)
This defines the modern standard of anesthetic care in pediatric ENT surgery.
Sources
- 1.Comparative Evaluation of Intravenous Versus Intranasal Dexmedetomidine on Emergence Delirium and Hemodynamics in Pediatric Patients Undergoing Adenotonsillectomy: A Randomized Controlled Trial. Frontiers in Pharmacology, 2025. Dai C, Zhao X, Li A, et al.
- 2.Intranasal Dexmedetomidine-Esketamine Combination Premedication Versus Monotherapy for Reducing Emergence Delirium and Postoperative Behavioral Changes in Pediatric Tonsillectomy and/or Adenoidectomy: A Randomized Controlled Trial. Drug Design, Development and Therapy, 2024. Liao Y, Xie S, Zhuo Y, et al.
- 3.Postanesthesia Care Unit Management. Gregory's Pediatric Anesthesia, 2020. Ames W, Kinder Ross A.
- 4.Procedural Sedation in Minor Procedure Rooms for Pediatric Myringotomy and Tympanostomy: A Quality Improvement Initiative. Otolaryngology–Head and Neck Surgery, 2022. Roy CF, Turkdogan S, Nguyen LHP, Yeung J.
- 5.Combined Intranasal Fentanyl and Dexmedetomidine Plus Inhaled Nitrous Oxide Sedation in Children Needing Myringotomy and Ventilation Tube Insertion With a Specific Handheld Device. International Journal of Pediatric Otorhinolaryngology, 2020. Trombetta A, Cossovel F, Grasso DL, Barbi E.
- 6.Tympanostomy Tube Placement in Children Using a Single-Pass Tool With Moderate Sedation. Otolaryngology–Head and Neck Surgery, 2017. Cofer S, Meyer A, Yoon D, et al.
- 7.A Randomized Controlled Trial Comparing Intranasal Midazolam and Chloral Hydrate for Procedural Sedation in Children. Otolaryngology–Head and Neck Surgery, 2015. Stephen MC, Mathew J, Varghese AM, Kurien M, Mathew GA.
- 8.Application of Oral Midazolam for Preoperative Sedation in Pediatric Tonsillectomy and Adenoidectomy and Its Effects on Emergence Delirium. European Archives of Oto-Rhino-Laryngology, 2026. Han P, Fan L, Tang F.
- 9.Precedex. FDA Drug Label. Food and Drug Administration. Updated May 20, 2026.
- 10.Best Evidence-Based Dosing Recommendations for Dexmedetomidine for Premedication and Procedural Sedation in Pediatrics: Outcome of a Risk-Benefit Analysis by the Dutch Pediatric Formulary. Paediatric Drugs, 2022. Freriksen JJM, van der Zanden TM, Holsappel IGA, Molenbuur B, de Wildt SN.
- 11.Population Pharmacokinetics of Intranasal Dexmedetomidine in Infants and Young Children. Anesthesiology, 2022. Li BL, Guan YP, Yuen VM, et al.
- 12.Safe pediatric procedural sedation and analgesia by anesthesiologists for elective procedures: A clinical practice statement from the European Society for Paediatric Anaesthesiology. Paediatric Anaesthesia, 2019. Zielinska M, Bartkowska-Sniatkowska A, Becke K, et al.
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